This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Specific Aims for Core A are: Aim 1. Provide administrative leadership and coordinate the overall research effort. Aim 2. Provide appropriate financial accounting, clerical, and other program management support. Aim 3. Establish and organize a group of established senior investigators who will serve as mentors for newly hired faculty working in the area of developmental biology. Aim 4. Manage and document the junior faculty mentoring process. Aim 5. Increase the research infrastructure and allow the implementation of new, state-of-the-art research equipment and technology centered on the project theme. Aim 6. Offer a source of expert outside consultation for optimization of research efforts in an individual and collective sense. Aim 7. Generate and insure the maintenance of cooperative, collaborative interactions between all components of this COBRE, and between other COBRE and K-INBRE centers and projects in Kansas.